Как преобразовать конкретную строку и столбец excel в набор данных?

I have used below code to convert excel to dataset.excel have(1,048,576 rows by 16,384 columns) in that time (Exception of type 'System.OutOfMemoryException' was thrown.) exception is thrown so i want to convert only 1000 rows and columns to dataset how to do it.
i understand to delete the empty columns and rows using (ctrl -) key but the user is not well knowledged in excel so i want to convert only 1000 rows and columns how to do it.

FileStream stream = File.Open(SourceUpload.Fullpath, FileMode.Open, FileAccess.Read);
IExcelDataReader excelReader = ExcelReaderFactory.CreateOpenXmlReader(stream);//xlsx file format
ds = excelReader.AsDataSet();